What hormone is known to decrease the desire to eat when fat stores are abundant?

Leptin is a hormone produced primarily by adipose (fat) tissue and plays a crucial role in regulating energy balance and body weight. When fat stores are sufficient, leptin levels increase, signaling the brain, particularly the hypothalamus, to reduce hunger and increase energy expenditure. This feedback mechanism is part of the body’s way of maintaining energy homeostasis.

As fat stores grow, leptin levels rise, which decreases appetite and encourages the body to use stored fat for energy, thus helping to prevent excessive weight gain. This is an important function of leptin in the regulation of body weight and metabolism.

In contrast, other hormones such as ghrelin are involved in stimulating appetite rather than suppressing it, and prolactin is linked more to reproductive functions than to appetite control. Amyloid-Beta is primarily associated with Alzheimer’s disease and cognitive functions, not directly with hunger regulation.