What neurodegenerative disorder is a major cause of dementia in the elderly characterized by the death of neurons?

Alzheimer's Disease is a major neurodegenerative disorder that significantly contributes to dementia, especially in the elderly population. This condition is characterized by the progressive death of neurons in the brain, which leads to cognitive decline, memory loss, and changes in behavior.

In Alzheimer's Disease, the formation of amyloid plaques and tau tangles is a key pathological hallmark. These abnormalities disrupt neuronal function and communication, ultimately resulting in cell death. This neurodegeneration primarily affects areas of the brain associated with memory and cognitive functions, such as the hippocampus and the cerebral cortex.

Understanding the mechanisms behind Alzheimer's Disease is crucial for developing potential treatments and interventions, as it is currently one of the most common causes of dementia. While other neurodegenerative disorders mentioned in the choices also lead to neurodegeneration, they have different primary effects and cause different types of cognitive and motor impairments.