Which brain network is activated during rest and self-referential thinking?

The Default Mode Network (DMN) is indeed the brain network that is most prominently activated during rest and self-referential thinking. This network is characterized by increased activity when a person is not focused on the external environment or performing goal-directed tasks. Instead, it is involved in processes such as daydreaming, recalling memories, envisioning the future, and reflecting on oneself.

Research has shown that when individuals engage in tasks that require introspection or self-related thought, the DMN becomes particularly active. This contrasts with networks like the Attention Network that is engaged in focused tasks requiring concentration, the Emotional Network that processes feelings and emotions, and the Motor Network which is involved in planning and executing physical movements. Therefore, the DMN's unique role in promoting internal thought processes solidifies its connection to rest and self-referential thinking.