Which gaseous neurotransmitter is involved in signaling processes?

Nitric oxide is recognized as a gaseous neurotransmitter that plays a unique role in signaling processes within the nervous system. Unlike traditional neurotransmitters, which are stored in vesicles and released into synaptic clefts, nitric oxide is synthesized on demand and diffuses across cell membranes due to its gaseous nature. This allows it to activate guanylate cyclase in nearby neurons and initiate a cascade of signaling events, ultimately influencing various physiological processes such as vasodilation, neurotransmitter release, and synaptic plasticity.

Additionally, nitric oxide contributes to cellular signaling by modulating the activity of other neurotransmitters, such as enhancing the release of neurotransmitters like glutamate. Its role in facilitating communication between cells highlights the importance of nitric oxide in the intricate network of neuronal interactions and its significant impact on brain function.